Literature Database Entry

debus2025blood


Lisa Y. Debus, Mario J. Wilhelm, Henri Wolff, Luiz C. P. Wille, Tim Rese, Michael Lommel, Jens Kirchner and Falko Dressler, " Blood Makes a Difference: Experimental Evaluation of Molecular Communication in Different Fluids," IEEE Transactions on Molecular, Biological and Multi-Scale Communications, August 2025. (online first)


Abstract

The experimental appraisal of existing molecular communication (MC) testbeds and modeling frameworks in real blood is an important step for future internet of bio-nano-things applications. In this paper, we experimentally compare the MC flow characteristics of water, blood substitute, and real porcine blood for a previously presented superparamagnetic iron oxide nanoparticles (SPION) MC testbed. We perform an extensive analysis of the system impulse response behavior of the testbed for the different fluids. Based on the identified MC flow characteristics, we extend an existing mathematical framework for our SPION testbed to capture the flow properties of blood. We evaluate its applicability to the collected data in comparison to two existing theoretical SIR models for MC in blood. In our work, we see that the added complexity of the transmission in blood opens up promising new possibilities to improve communication through the human circulatory system.

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Lisa Y. Debus

Mario J. Wilhelm

Henri Wolff

Luiz C. P. Wille

Tim Rese

Michael Lommel

Jens Kirchner

Falko Dressler

BibTeX reference

`@article{debus2025blood,

author = {Debus, Lisa Y. and Wilhelm, Mario J. and Wolff, Henri and Wille, Luiz C. P. and Rese, Tim and Lommel, Michael and Kirchner, Jens and Dressler, Falko},

doi = {10.1109/TMBMC.2025.3602650},

note = {to appear},

title = {{Blood Makes a Difference: Experimental Evaluation of Molecular Communication in Different Fluids}},

journal = {IEEE Transactions on Molecular, Biological and Multi-Scale Communications},

issn = {2332-7804},

publisher = {IEEE},

month = {8},

year = {2025},

} `